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Magnesium Glycinate Powder

Chelated magnesium bound to glycine for enhanced absorption, supporting relaxed sleep, stress management, and muscle function.

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Magnesium Glycinate Powder

Chelated magnesium bound to glycine for enhanced absorption, supporting relaxed sleep, stress management, and muscle function.

(23 Reviews) Write a Review

View All Reviews

Available in multiple forms! Click Here for:
  • Chelated With Glycine For Better Uptake
  • Gentle On Stomach Unlike Other Forms
  • Supports Deep Restorative Sleep Quality
  • Essential For 300+ Enzyme Systems

3rd Party Lab Tested & Verified

See Why ND Magnesium Is The Best

Evidence-Based, Fact-Checked

Updated On: 05/05/2026

$16.99 - $22.99

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Benefits

When You'll Notice Effects

2-3 Weeks (With Immediate Effects)

Magnesium Glycinate is a vital mineral supplement essential for over 300 enzyme systems. It may improve sleep quality, support stress management, and enhance cognitive function.

  • Sleep Sleep
  • Cognition Cognition
  • Stress Stress
  • Mood Mood

WHY ND MAGNESIUM GLYCINATE?

The MOST Bioavailable Magnesium with Zero Digestive Upset
test

How To Take

Dose
Dose

1600mg (Per Serving)

Timing
Timing

Night

How to Take
How to Take

With Or Without Food

Frequency
Frequency

1 Time Daily

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  • About Magnesium Glycinate Powder

    Magnesium Glycinate Fully Chelated text overlay on a background of nutrient-rich foods, including leafy greens, avocado, seeds, beans, and yogurt.

    Our Magnesium Glycinate Powder delivers a highly bioavailable form of this essential mineral that supports over 300 enzyme systems in your body. The chelated form binds magnesium to the amino acid glycine, enhancing absorption while being gentle on your digestive system. It supports muscle relaxation, healthy sleep quality, and overall wellness without the gastrointestinal discomfort often associated with other magnesium forms.

    Our Magnesium Glycinate Story

    Traditional magnesium supplements have a fundamental problem: poor absorption rates that leave many people still deficient despite regular supplementation. Standard magnesium forms like oxide often cause digestive upset and pass through the system without being properly utilized by the body. The gap between taking magnesium and actually benefiting from it drove us to seek a better solution.

    Chelation technology became our focus, where magnesium binds to glycine to create a stable, highly absorbable complex. The chelated form not only improves bioavailability but also leverages glycine's own calming properties to enhance the overall effectiveness for stress management and sleep support. We provide this superior form in a convenient powder format that allows for flexible dosing and easy mixing.

    Benefits

    • Supports Sleep: Promotes muscle relaxation and nerve function, helping you achieve better sleep quality and reduced muscle tension through magnesium's calming effects on the nervous system.
    • Improves Cognition: Supports various aspects of brain health including memory, focus, and information processing speed through magnesium's role in neurotransmitter function and neuroprotection.
    • Supports Stress Levels: Helps regulate the body's stress response and promotes a sense of calm and relaxation, with research suggesting it reduces anxiety symptoms and improves resilience to stressful situations.
    • Supports Mood: Contributes to emotional balance through magnesium's involvement in over 300 enzyme systems that regulate mood-related neurotransmitters and nervous system function.

    The glycine component of this chelated form provides additional calming benefits, working with magnesium to support relaxation pathways. This dual-action approach makes magnesium glycinate particularly effective for evening use, supporting both physical and mental unwinding while maintaining gentle digestive tolerance.

    Comparison of Nootropics Depot Magnesium Glycinate capsules and Magnesium Oxide, highlighting benefits like high absorption and sleep support versus poor bioavailability and laxative effects.

    Quality and Standardization

    • Rigorous Testing Standards: Our Magnesium Glycinate undergoes thorough quality control checks to ensure purity and potency, with detailed Certificates of Analysis (CoA) provided for complete transparency.
    • Superior Raw Materials: We carefully select the best raw materials and use state-of-the-art manufacturing processes to ensure that every serving meets our high standards for quality and consistency.
    • GMP Compliance: We adhere to Good Manufacturing Practices (GMP) with regularly inspected facilities to maintain the highest quality standards throughout production.
    • Expert Quality Assurance: Our team of chemists and nutritionists work tirelessly to ensure that our Magnesium Glycinate delivers consistent potency and purity backed by rigorous scientific standards.

    Man relaxing on a recliner with text promoting Magnesium Glycinate for muscle relaxation and recovery support.

    Mechanism of Action

    • Chelated Absorption: The glycine component acts as a carrier for magnesium, enhancing bioavailability by allowing absorption as an intact dipeptide in the small intestine via specialized transport pathways.
    • pH Buffering: Glycine acts as an excellent pH buffer, significantly reducing the pH increase at tight junctions that typically hinders magnesium absorption in standard forms.
    • Neurotransmitter Support: Glycine functions as an inhibitory neurotransmitter, contributing to the calming effects often reported with magnesium glycinate supplementation.
    • Enzymatic Cofactor: Magnesium serves as a cofactor in over 300 enzyme systems, regulating biochemical reactions including protein synthesis, muscle and nerve function, and energy production through oxidative phosphorylation and glycolysis.
    • Cellular Structure and Function: Magnesium contributes to bone structural development and is required for the synthesis of DNA, RNA, and the antioxidant glutathione.

    Overview of the Science

    Research on magnesium glycinate has shown promising results across various areas of health and wellness. Studies suggest that this highly bioavailable form of magnesium may offer benefits for sleep quality, stress management, and cognitive function. Several clinical trials have demonstrated that magnesium supplementation can improve sleep parameters, including sleep efficiency and onset latency [1][2][3]. This is particularly notable in older adults and individuals with sleep disturbances. The mechanism appears to be related to magnesium's role in regulating neurotransmitters and melatonin production.

    In terms of stress management, magnesium glycinate has been shown to help regulate stress hormones and support the body's stress response. Some studies have found that magnesium supplementation may reduce anxiety symptoms and improve resilience to stressful situations [4][5][6]. Cognitive function is another area where magnesium glycinate shows potential. Research indicates that it may support various aspects of brain health, including memory, attention, and information processing speed [7][8][9]. This could be due to magnesium's involvement in neurotransmitter function and its neuroprotective properties.

    While magnesium glycinate shows promise on its own, some studies suggest that combining it with other supplements may offer synergistic benefits. For instance, pairing it with Bacopa Monnieri might enhance cognitive performance, while combining it with L-Theanine could provide additional support for stress management and relaxation.

    [1] Mah J, Pitre T. Oral magnesium supplementation for insomnia in older adults: a systematic review & meta-analysis. BMC Complement Med Ther. 2021;21(1):125.

    [2] Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, Rashidkhani B. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci. 2012;17(12):1161-1169.

    [3] Hausenblas HA, Lynch T, Hooper S, Shrestha A, Rosendale D, Gu J. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial. Sleep Med X. 2024;8:100121.

    [4] Rawji A, Awan S, Rana J, Mourtzanakis K, Peltier MR. Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review. Cureus. 2024;16(4):e57876.

    [5] Boyle NB, Lawton C, Dye L. The effects of magnesium supplementation on subjective anxiety and stress—a systematic review. Nutrients. 2017;9(5):429.

    [6] Pouteau E, Kabir-Ahmadi M, Noah L, Mazur A, Dye L, Hellhammer J, Pickering G, Dubray C. Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial. PLoS One. 2018;13(12):e0208454.

    [7] Liu G, Weinger JG, Lu ZL, Xue F, Sadeghpour S. Efficacy and safety of MMFS-01, a synapse density enhancer, for treating cognitive impairment in older adults: a randomized, double-blind, placebo-controlled trial. J Alzheimers Dis. 2016;49(4):971-90.

    [8] Slutsky I, Abumaria N, Wu LJ, Huang C, Zhang L, Li B, Zhao X, Govindarajan A, Zhao MG, Zhuo M, Tonegawa S, Liu G. Enhancement of learning and memory by elevating brain magnesium. Neuron. 2010;65(2):165-77.

    [9] Zhang C, Hu Q, Li S, Dai F, Qian W, Hewlings S, Yan T, Wang Y. A Magtein®, magnesium L-threonate, -based formula improves brain cognitive functions in healthy Chinese adults. Nutrients. 2022;14(24):5235.

    Nootropics Depot Magnesium Glycinate 800mg capsules in blue bottles with product benefits highlighted: unmatched bioavailability, promotes deep rest, supports cellular health, and gentle on digestion.


    Click here to read the Research Snapshot

    Ingredients

    Magnesium Bisglycinate Chelate Monohydrate:

    • 1,600mg per serving (1 scoop)
    • Provides 200mg elemental magnesium (50% DV)
    • Chelated form for enhanced absorption

    This chelated form of magnesium binds the mineral to glycine amino acids, creating a stable complex that resists interference from other nutrients and stomach acid. The bisglycinate chelate structure allows magnesium to bypass typical absorption barriers in the intestines, delivering superior bioavailability compared to standard magnesium salts like oxide or sulfate. Each serving provides 200mg of elemental magnesium in a gentle, well-tolerated form that supports muscle relaxation and sleep quality without digestive discomfort.

The Science

What Our Scientific Board Does

The Process

What Do They Do?

  • Review Product Claims
  • Review Cited Research
  • Suggest Changes to Claims
  • Approves Final Conclusions
See The Process

Overview Of The Scientific Evidence

Our Research Snapshot

What Does The Research Show?

Magnesium glycinate may boost sleep, stress resilience, cognitive performance, and mood according to available research.

Understand The Evidence

Trust Through Transparency

Your health matters, which is why we only use the best 3rd party ISO accredited labs and cGMP certified and FDA registered facilities right here in the USA

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Magnesium Glycinate Powder

Magnesium Glycinate Powder

$16.99 - $22.99