L-Citrulline vs. L-Citrulline DL-Malate: Which Is Best?

L-Citrulline vs. L-Citrulline DL-Malate: Which Is Best?

Posted by Nootropics Depot on 22nd Apr 2020

L-CITRULLINE VS. L-CITRULLINE DL-MALATE: WHICH VERSION IS BEST?

There are three dietary amino acids involved in the urea cycle: L-Citrulline, L-ornithine and L-arginine. L-Citrulline turns into arginine when it enters the body, making it a potentially beneficial supplement for supporting your arginine levels.

Citrulline is found in a variety of foods. Watermelons in particular carry the highest natural concentration of Citrulline where it’s present in both the fruit’s meat and the rind! Citrulline is also present in some legumes such as, garbanzo beans, soy, and peanuts. In terms of meat, it’s found in high concentrations in the liver but in smaller amounts in red meat and salmon.

Since the concentration of L-Citrulline varies in foods, many look towards supplementation to increase the amount of L-Citrulline in the body. Some use L-Citrulline in various forms, while others use L-citrulline DL-Malate. By looking deeper into how these two compounds work, we can determine which of the two might work best for you.

HOW DOES CITRULLINE WORK?

As discussed, Citrulline is a critical precursor to arginine. Arginine then converts to nitric oxide and more Citrulline by nitric oxide synthase.

You may ask yourself "wouldn’t taking arginine supplements increase arginine levels?" The answer is found in arginase, which is an enzyme found in the stomach and intestines. Arginase breaks down arginine directly into ornithine and urea, neither of which are involved in forming nitric oxide. Arginine supplements break down in the stomach and intestines before getting absorbed and reaching the blood. Arginine supplements may elevate levels initially, but the effect will taper off quickly. Citrulline and Citrulline Malate supplements promote the levels of arginine in your plasma over a longer period of time.

L-CITRULLINE VS. L-CITRULLINE DL-MALATE: WHICH VERSION IS BEST?

There are three dietary amino acids involved in the urea cycle: L-citrulline, L-ornithine and L-arginine. L-Citrulline turns into arginine when it enters the body, making it a potentially beneficial supplement for supporting your arginine levels.

Citrulline is found in a variety of foods. Watermelons in particular carry the highest natural concentration of Citrulline where it’s present in both the fruit’s meat and the rind! Citrulline is also present in some legumes such as, garbanzo beans, soy, and peanuts. In terms of meat, it’s found in high concentrations in the liver but in smaller amounts in red meat and salmon.

Since the concentration of L-citrulline varies in foods, many look towards supplementation to increase the amount of L-citrulline they ingest. Some use L-citrulline in various forms, while others use L-citrulline DL-malate. By looking deeper into how these two compounds work, we can determine which of the two might work best for you.

L-CITRULLINE VS. L-CITRULLINE DL-MALATE: WHICH VERSION IS BEST?

There are three dietary amino acids involved in the urea cycle: L-citrulline, L-ornithine and L-arginine. L-Citrulline turns into arginine when it enters the body, making it a potentially beneficial supplement for supporting your arginine levels.

Citrulline is found in a variety of foods. Watermelons in particular carry the highest natural concentration of Citrulline where it’s present in both the fruit’s meat and the rind! Citrulline is also present in some legumes such as, garbanzo beans, soy, and peanuts. In terms of meat, it’s found in high concentrations in the liver but in smaller amounts in red meat and salmon.

Since the concentration of L-citrulline varies in foods, many look towards supplementation to increase the amount of L-citrulline they ingest. Some use L-citrulline in various forms, while others use L-citrulline DL-malate. By looking deeper into how these two compounds work, we can determine which of the two might work best for you.

As discussed, citrulline is a critical precursor to arginine. Arginine then converts to nitric oxide and more citrulline by nitric oxide synthase.

Well wouldn’t taking arginine supplements increase arginine levels? The answer is found in arginase, which is an enzyme found in the stomach and intestines. Arginase breaks down arginine directly into ornithine and urea, which both are not involved in forming nitric oxide. Arginine supplements break down in the stomach and intestines before getting absorbed and reaching the blood. Arginine supplements may elevate levels initially, but the effect will taper off quickly. Citrulline and citrulline malate supplements promote the levels of arginine in your plasma over a longer period of time.

Urea Cycle Diagram

As discussed, citrulline is a critical precursor to arginine. Arginine then converts to nitric oxide and more citrulline by nitric oxide synthase.

Well wouldn’t taking arginine supplements increase arginine levels? The answer is found in arginase, which is an enzyme found in the stomach and intestines. Arginase breaks down arginine directly into ornithine and urea, which both are not involved in forming nitric oxide. Arginine supplements break down in the stomach and intestines before getting absorbed and reaching the blood. Arginine supplements may elevate levels initially, but the effect will taper off quickly. Citrulline and citrulline malate supplements promote the levels of arginine in your plasma over a longer period of time.

Urea Cycle Diagram

L-CITRULLINE DL-MALATE BENEFITS

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✔ PROMOTES ENERGY*

 

✔ SUPPORTS CARDIOVASCULAR HEALTH*

 

✔ SUPPORTS MEMORY*

 

✔ SUPPORTS A HEALTHY METABOLISM*

 

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✔ PROMOTES ENERGY*

 

✔ SUPPORTS CARDIOVASCULAR HEALTH*

 

✔ SUPPORTS MEMORY*

 

✔ SUPPORTS A HEALTHY METABOLISM*

 

Research shows Citrulline and its effects on arginine levels may increase nitric oxide levels and may also support cardiovascular health. The molecular compound nitric oxide aids in transmitting signals to the cells allowing for intercellular communication. Nitric oxide is a molecular compound that’s primarily involved in helping cells transmit signals, allowing for effective cell to cell communication. Nitric oxide also helps support circulation. This effect contributes to Citrulline’s impact on blood flow, promoting cardiovascular health, and supporting the immune system.

Because of its potential for muscle-building benefits, nitric oxide is popular among athletes. The increase in blood flow may promote muscle recovery quicker as well as achieve growth. The blood flow may also deliver more nutrients to the muscle tissue. Research conducted on cyclists suggested that nitric oxide may promote endurance and support longer training sessions by combating lactic acid buildup, which is the cause of muscle fatigue.

Neural functions such as short and long term memory may be enhanced with the increase of circulation from Citrulline and nitric oxide. This may result in promoting both short- and long-term, and memory recall.

L-Citrulline may also support your metabolism. Studies indicate that L-Citrulline may contribute to increased strength and leaner, larger muscles. This may support efforts in losing weight.

L-Citrulline Structure


WHAT IS CITRULLINE DL-MALATE?

L-Citrulline DL-malate is Citrulline with a malic acid component added to it. Malate, also known as malic acid, is a compound that occurs naturally in many fruits. It is mostly used as a food additive or preservative.

The combination of Citrulline and malic acid has been shown to promote better absorption and increased bioavailability. However, some studies have shown that malic acid, on its own, has demonstrated potential to support pain management and promote increased physical energy. Many skincare products also include malic acid for its potential exfoliating properties.

"Research has shown that magnesium levels are decreasing in most foods... With the magnesium content decreasing in crops and the increase in the consumption of processed foods, magnesium deficiencies in the population are becoming more prevalent."

Malic Acid Structure


CHOOSING BETWEEN CITRULLINE AND CITRULLINE DL-MALATE

For most people, the preferred natural nootropic tends to be L Citrulline DL Malate since it may increase arginine and nitric oxide levels while also promoting energy output from the malic acid. This offers a double benefit that many bodybuilders and athletes look for. However, if you aren’t looking for the energy promoting and other benefits from malic acid, then Citrulline may be beneficial for you on its own. The choice ultimately comes down to what each person’s individual needs are.

Why Choose Citrulline Malate With A 2:1 Ratio?

Some dietary supplement vendors will offer Citrulline Malate with more malic acid than Citrulline. This imbalanced ratio may lower the quality of effects. The recommendation is that you find Citrulline Malate with a two to one ratio, meaning twice the grams of Citrulline for every gram of malate. You can find L-Citrulline DL-Malate 2:1 Powder at Nootropics Depot, ensuring a proper ratio in this nootropic supplement.


TOP RECOMMENDED L-CITRULLINE DL-MALATE STACKS

ENERGY / PRE-WORKOUT STACK

Dynamine Methylliberine Capsules

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Chocamine Cocoa Extract

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Great for those looking for a fast acting high energy pre workout stack to help get the most out of a workout and keep energy levels high til the end.

CARDIOVASCULAR SUPPORT STACK

Dynamine Methylliberine Capsules

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Chocamine Cocoa Extract

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This combination helps promote the overall production of nitric oxide. Nitric oxide promotes blood flow throughout the body and brain, thus promoting cardiovascular function and supporting balanced inflammation levels.

STRENGTH + ENDURANCE STACK

Dynamine Methylliberine Capsules

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Caffeine + L-Theanine Capsules

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The energy promoting properties of Creatine and L-Citrulline DL-Malate combined with enhanced Nitric oxide production make for a potent blend of both power and longevity for intense workouts.

If you like these stacks, and would like to discover more stacks like these, then check out our free stack guides! The stack guides contain 70+ stacks just like these, split into beginner, intermediate and advanced stacks. Check it out here!


ADVANCED L-CITRULLINE DL-MALATE PRE-WORKOUT STACK

The Dynamine Methylliberine in this pre-workout mix will take effect rapidly and in conjunction with CoQ10, Cordyceps 10:1 and Caffeine with L- Theanine. It will help support your endurance through long workouts. Creatine taken daily, and Citrulline DL Malate, helps promote strength and endurance. This is a simple, no-frills pre-workout formulation. Try it and share your experience with us!

Dynamine Methylliberine Capsules

100mg of Dynamine Methylliberine can help boost energy and mood levels very quickly and launch you right into your workout routine.

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L-Citrulline DL-Malate Powder

3-6 grams helps produce nitric oxide boosting effects. Nitric oxide helps enhance blood flow, which may increase endurance and muscle growth.

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L-Citrulline DL-Malate Powder

5 grams of Creatine taken long term may help enhance strength. Creatine monohydrate may increase hydration before workouts as well as help make ATP.

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CoQ10 Powder

200mg of CoQ10 may increase energy levels. CoQ10 in conjunction with creatine may also help increase ATP production.

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Cordyceps Mushroom Extract Capsules

A dosage of 250mg. Cordyceps may help promote endurance, while also providing a notable mood boost.

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Caffeine + L-Theanine Capsules

One capsule of the formula contains 100mg of Caffeine and 200mg of L-Theanine. Helping to further solidify the energy promoting effects of this comprehensive pre-workout stack!

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BUY L-CITRULLINE DL-MALATE SUPPLEMENTS FROM NOOTROPICS DEPOT

Dynamine Methylliberine Powder

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Scoops: Nootropics Depot does not provide scoops or spoons with any of our products. Scoops are highly unreliable for accurate measuring. Scoops measure volume rather than weight which is problematic because all powders have different densities. A milligram scale is needed to accurately measure powder products.

Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About Nootropics Depot

Nootropics Depot is an online-based vendor of high quality nootropics, novel plant extracts, amino acids, fish oil, choline supplements, vitamins, and more based in Tempe Arizona. We were founded in 2013 when we realized the industry needed a trusted source for these products and someone to champion the change the supplement industry needs. We have our own in-house analytical testing lab with some of the best analytical chemists in the supplement industry. We are constantly striving to advance and improve the purity and analytical standards of not only the nootropics industry, but the larger supplement industry as a whole.