Kaneka Ubiquinol: Introducing A Bioavailable and Crystal-Free Reduced CoQ10 Supplement

What Is CoQH-CF?

A completely soluble, 100% crystal-free formulation of CoQ₁₀ in the Ubiquinol form, with clinically-proven and superior bioavailability.

CoQH-CF is a unique formulation of Coenzyme Q₁₀ (CoQ₁₀), an important coenzyme that plays a major role in many functions throughout our body. You may already be familiar with one of our other CoQ₁₀ softgel formulations called CoQsol-CF which we have written about in this blog. The difference between CoQsol-CF and CoQH-CF is that CoQsol-CF is made with the oxidized form of CoQ₁₀ called ubiquinone whereas CoQH-CF is made with the reduced form of CoQ₁₀ called ubiquinol.

There are some key differences between the two that set them apart. However, for this blog we will solely focus on what ubiquinol and more specifically, CoQH-CF does. We will have a blog discussing the key differences between ubiquinone and ubiquinol in the near future however, so keep an eye out for the comparison blog!

CoQH-CF uses a very high-quality form of Ubiquinol made by Kaneka. Kaneka produces this Ubiquinol from yeast derived Ubiquinone resulting in a bio-identical Ubiquinol supplement. In isolation, Kaneka Ubiquinol has already been shown to have good bioavailability, however, Soft Gel Technologies figured out how to further enhance this already impressive bioavailability. The technology behind the bioavailability enhancement is very well thought out and has been shown to drastically enhance Ubiquinol absorption.

The first step in enhancing Ubiquinol CoQ₁₀ bioavailability involves controlling the crystallization of Ubiquinol CoQ₁₀. The size of the crystals that Ubiquinol CoQ₁₀ can form, in combination with its low water solubility, means that crystal size and shape will drastically affect bioavailability. There are multiple strategies that are used to overcome this limitation such as micronizing the powder or turning it into a paste. However, none of these methods fully eliminate the crystals in Ubiquinol CoQ₁₀, and due to this, maximum bioavailability cannot be achieved. The best way to take crystal size and form out of the equation is to fully solvate the Ubiquinol CoQ₁₀. This is quite hard, however, as Ubiquinol is not soluble in most common solvents such as water or glycerin. Soft Gel Technologies looked towards citrus fruits for a solution and landed on a unique citrus-based solvent called D-Limonene.

What is D-Limonene And Why Is It An CoQH-CF Ingredient?

D-Limonene is a terpene that is found in high concentrations in the peels of various citrus fruits. Lemons contain a particularly high concentration of D-Limonene and this is also where D-Limonene gets its name from. It’s safe for human consumption and even has some unique benefits of its own. D-Limonene may help promote liver health and metabolic health while also having a minor calming and stress-regulation effect. More importantly however, D-Limonene is a fantastic natural solvent that can be used to fully solvate Ubiquinol CoQ₁₀ crystals. Furthermore, D-Limonene also has the ability to prevent Ubiquinol CoQ₁₀ from re-crystallizing in solution.

Once the Ubiquinol CoQ₁₀ is dissolved in the D-limonene, it is now crystal free, which is designated in the name CoQH-CF, where the CF stands for ‘Crystal Free.' The crystal free nature of the product significantly aids in absorption, in addition to consistency of absorption. Furthermore, the CoQ₁₀ is now in solution and D-Limonene is absorbed rapidly by the body. This further increases the overall bioavailability of Ubiquinol CoQ₁₀.

Why Is Alpha Lipoic Acid An CoQH-CF Ingredient?

The last issue that Soft Gel Technologies had to overcome, is the fact that Ubiquinol can oxidize and turn into Ubiquinone. To prevent this, Soft Gel Technologies added Alpha Lipoic Acid dissolved in capric and caprylic acid to prevent the Ubiquinol CoQ10 from oxidizing. The full solubility and matrix that Soft Gel Technologies developed makes CoQH-CF one of the best iterations of a Kaneka Ubiquinol product available on the market. CoQH-CF is exceptionally stable and has unrivaled bioavailability. If you would like to take advantage of the plethora of Ubiquinol CoQ₁₀ benefits, CoQH-CF should be your primary choice! Speaking of Ubiquinol benefits, what exactly are they? The rest of this article, will describe in depth, four of our favorite CoQH-CF benefits which are:

• • May help promote healthy levels of oxidation
  • May help promote cellular energy
  • May help promote healthy cardiovascular function
  • May help replenish ubiquinol stores

Ubiquinol is naturally present in our bodies and one of its main purposes is to minimize the impacts of oxidative stress. Under normal conditions, this means that we are protected from a host of oxidative processes, which can have deleterious effects on our bodies and brains. As we age CoQ₁₀ levels lesen, and more specifically, our bodies have a harder time converting Ubiquinone into Ubiquinol. Since Ubiquinol is the main oxidation-regulating form of CoQ₁₀, decreased levels of Ubiquinol could mean an increase in oxidative stress.

After Ubiquinol levels start to lessen, it may impact our overall cardiovascular, metabolic and brain health. By supplementing with a high quality Ubiquinol CoQ₁₀ supplement, such as CoQH-CF, you can help increase your bodies own oxidation defenses. The overall net-effect this may have is a reduced rate of aging, cardiovascular health support, and cognitive function support. This means that Ubiquinol is a fantastic supplement to take as we get older.

A more in-depth analysis of the oxidation-regulating effects of Ubiquinol reveals some other interesting Ubiquinol benefits. One of the more interesting Ubiquinol benefits is that Ubiquinol may regulate the oxidation of LDL cholesterol, the “bad cholesterol”. When LDL cholesterol oxidizes, it can become very damaging to our cardiovascular system. This is one of the reasons why keeping cholesterol, and especially LDL cholesterol low, is important for optimum health. However, LDL cholesterol also has some vital functions throughout the body, such as transporting fats around the body, so we also cannot lower LDL too much. What we can do is ensure our LDL levels are in their optimal range and then supplement with Ubiquinol CoQ₁₀ to help protect LDL cholesterol from oxidative stress.

CoQ₁₀ may also help increase mitochondrial function, and through this mechanism, enhance energy levels through enhanced ATP production. Mitochondria are also very susceptible to oxidation as a lot of oxidative free radicals are produced within mitochondria. Ubiquinol may help prevent oxidative damage to mitochondria, thereby further enhancing mitochondrial function. By enhancing mitochondrial function, we can enhance our physical performance and enhance overall vitality!

"As we age CoQ₁₀ levels lessen, and more specifically, our bodies have a harder time converting Ubiquinone into Ubiquinol. Since Ubiquinol is the main oxidation-regulating form of CoQ₁₀, decreased levels of Ubiquinol could mean an increase in oxidative stress."

As we briefly touched on in the section about oxidation, CoQ₁₀ plays an important role in our mitochondria. CoQ₁₀ can switch back and forth between Ubiquinone and Ubiquinol, and this reduction/oxidation (REDOX) reaction helps produce cellular energy in the form of ATP.

Within the Mitochondria, lies a system which produces the cellular energy our body needs. This system is called the Electron Transport Chain (ETC) and CoQ₁₀ plays a vital role in the ETC. CoQ₁₀ has the ability to accept electrons, and shuttle them through the ETC. In addition to this, CoQ₁₀ helps create a proton gradient within the ETC which is ultimately what creates ATP. By supplementing with Ubiquinol CoQ₁₀, you can both increase mitochondrial function and overall mitochondrial health.

ATP demand is much higher in highly metabolic organs such as the heart and brain and this is where CoQ₁₀ will exert some of its most beneficial effects. By keeping the energy centers of these organs safe from oxidative damage and by enhancing their function, CoQH-CF may help enhance the health of these organs. The net effect this may have is enhanced full body health!

As we have already discussed, CoQ₁₀ is an essential component of overall health as it is used to produce the energy that is vital for organ function. The heart, in particular, has a very high concentration of mitochondria and CoQ_10. So it is important for overall cardiovascular health that adequate levels of CoQ₁₀ are maintained. By supplementing with CoQ₁₀, we may be able to help our heart perform at optimal levels by providing it with the energy that it needs. In fact, research has shown that CoQ₁₀ is a highly beneficial supplement for maintaining overall cardiovascular health. As we discussed earlier, Ubiquinol CoQ₁₀ may also help protect us from oxidized LDL which does not support cardiovascular health.

Furthermore, Ubiquinol CoQ₁₀ may also help enhance blood flow. This effect may be attributed to it oxidation-regulating effects which can help preserve levels of nitric oxide in our blood vessels. Nitric oxide has the ability to relax the walls of our blood vessels, a process known as vasodilation. By increasing vasodilation, CoQH-CF may be able to optimize blood flow which may help enhance overall cardiovascular function even further.

Overall, CoQH-CF would be a fantastic product to take if you want to help optimize your cardiovascular function. This can be beneficial for a wide range of individuals such as athletes or just those seeking a little bit more vitality.

One of the hallmarks of aging is a loss of total CoQ₁₀, and more specifically, a loss of Ubiquinol. Research has shown that individuals over the age of 40 may already start experiencing decreased stores of CoQ₁₀ and Ubiquinol. As has become clear throughout this article, maintaining adequate CoQ₁₀ levels is very important to supporting optimal health. With this in mind, we would particularly suggest CoQH-CF supplementation to people over the age of 40. That being said, anyone who is 18 or older can benefit greatly from enhancing their CoQ₁₀ stores, and more specifically, their Ubiquinol stores.

If you are above the age of 40, replenished Ubiquinol stores may give you a restored sense of vitality. You will have more daytime energy and have an easier time getting in some solid physical exercise. Furthermore, enhanced Ubiquinol stores may also help enhance cognitive function which is always a fantastic added bonus!

For those under the age of 40, replenishing Ubiquinol stores can still have benefits. For example, it has been shown that CoQ₁₀ may help with headaches, muscle function and mood. This makes CoQH-CF a very versatile supplement and no matter what your age, you can benefit from adding a CoQH-CF supplement to your daily supplement regime!

Since CoQH-CF is a solubilized form of Ubiquinol, it matters much less whether you take it with our without food. This makes dosing easy and consistent as the CoQH-CF will absorb reliably and consistently. In addition to its highly enhanced bioavailability, the enhanced ease of dosing makes this one the the best ubiquinol supplement currently out on the market.

CoQH-CF Recommended Dosage

The recommended Ubiquinol dose, as is contained in CoQH-CF is set at 100 mg per dose. This will provide you with a large Ubiquinol dose, allowing you to experience all of the Ubiquinol benefits to their fullest potential!